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Feline plasma cell pododermatitis: a study of 8 cases.
Patrícia Dias Pereira1, Augusto M R Faustino
1ICBAS - Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Largo Prof Abel Salazar, Porto 4099-003, Portugal.
Veterinary Dermatology
|December 18, 2003
Summary
Feline plasma cell pododermatitis, a footpad swelling and ulceration condition in cats, showed no breed or age predisposition. Histological analysis revealed numerous plasma cells, with successful treatment via glucocorticoids or surgical excision.
Area of Science:
- Veterinary Pathology
- Immunohistochemistry
- Feline Medicine
Background:
- Feline plasma cell pododermatitis is an uncommon condition affecting cats' footpads.
- Understanding its histopathology and treatment outcomes is crucial for veterinary care.
Purpose of the Study:
- To investigate the histological and immunohistochemical features of feline plasma cell pododermatitis.
- To evaluate treatment responses in affected cats.
Main Methods:
- Histological (hematoxylin and eosin) and histochemical (methyl green-pyronin) staining were performed.
- Immunohistochemistry using antibodies against lambda light chains of immunoglobulins was utilized.
- Clinical data and treatment outcomes were retrospectively analyzed for eight feline cases.
Main Results:
- Lesions were characterized by a significant infiltrate of plasma cells, primarily in a perivascular pattern.
- No specific predisposition regarding sex, breed, age, or paw location was identified.
- Binucleated plasma cells and mitotic figures were observed within the lesions.
Conclusions:
- Feline plasma cell pododermatitis presents histologically with abundant plasma cells.
- Both glucocorticoid therapy and surgical excision demonstrated efficacy in achieving remission.
