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Difference in gene expression profiles between human CD4+CD25+ and CD4+CD25- T cells
Nirupma Pati1, Soumitra Ghosh, Martin J Hessner
1Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, Medical College and Children's Hospital of Wisconsin, Milwaukee, Wisconsin 53226, USA.
Annals of the New York Academy of Sciences
|December 18, 2003
Abstract:
We studied the gene expression profiles of human CD4+CD25+ and CD4+CD25- T cells by using cDNA microarrays. Our preliminary results indicate that there are likely significant differences in the regulation of apoptosis, cell cycle, cytokine receptor, cell-cell interaction, and stress pathway genes between these two subtypes of T cells.
