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Ulcerative colitis associated enteritis: is ulcerative colitis always confined to the colon?
Joel Rubenstein1, Ahmed Sherif, Henry Appelman
1Division of Gastroenterology, University of Michigan Medical Center, 3912 Taubman Center, Box 0362, Ann Arbor, MI 48109-0362, USA.
Journal of Clinical Gastroenterology
|December 18, 2003
Summary
Ulcerative colitis (UC) can rarely affect the small intestine, presenting as ulcerative enteritis. This condition, distinct from Crohn disease, often appears post-colectomy and responds to standard inflammatory bowel disease therapies.
Area of Science:
- Gastroenterology
- Pathology
Background:
- Ulcerative colitis (UC) is a chronic colonic inflammatory disease with unknown causes.
- Small bowel involvement in UC is exceptionally rare, prompting diagnostic reconsideration.
Observation:
- A 38-year-old man developed severe diarrhea post-colectomy for UC.
- Histological examination revealed ulcerative enteritis with features mirroring UC.
Findings:
- This study reviews 11 additional cases of UC-associated enteritis (UCAE).
- UC-associated enteritis is distinct from Crohn disease.
- UCAE frequently manifests shortly after colectomy.
- UCAE typically responds to standard inflammatory bowel disease treatments.
Implications:
- Recognizing UCAE is crucial for accurate diagnosis and management.
- This entity expands the understanding of ulcerative colitis manifestations.
- Further research into the pathogenesis of UCAE is warranted.
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