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Identification and management of vascular risk: beyond low density lipoprotein cholesterol
Joyce L Ross1, Margaret A Manuszak, Joy E Wachs
1Cardiovascular Risk Intervention Program, University of Pennsylvania Health Systems, Philadelphia Heart Institute, Philadelphia, USA.
Insights
Vascular disease assessment requires a multifactorial approach beyond traditional cholesterol levels. Novel risk factors, combined with existing ones, can improve prevention and treatment strategies for this inherited metabolic condition.
Area of Science:
- Cardiovascular Medicine
- Metabolic Diseases
- Preventive Healthcare
Background:
- Vascular disease is a pervasive inherited metabolic condition.
- Traditional assessment methods, primarily focusing on blood cholesterol, are insufficient for identifying at-risk individuals.
- Eighty percent of individuals with vascular disease share similar cholesterol levels with those unaffected.
Purpose of the Study:
- To advocate for a multifactorial approach in vascular disease assessment.
- To highlight the utility of novel risk factors in conjunction with traditional ones.
- To emphasize the role of occupational health nurses in vascular disease prevention and management.
Main Methods:
- Review of current literature on vascular disease risk factors.
- Discussion of available assays for novel risk factor determination.
- Exploration of the occupational health nurse's role in long-term client management.
Main Results:
- Novel risk factors are additive and, when combined with traditional factors, allow for targeted low-density lipoprotein (LDL) adjustment.
- These factors are crucial for identifying appropriate treatment protocols to halt disease progression in affected individuals.
- Current healthcare practices often fail to adequately identify and treat cardiovascular risk.
Conclusions:
- A multifactorial assessment strategy is prudent for vascular disease.
- Occupational health nurses are uniquely positioned to facilitate client trust and adherence to prevention and treatment goals.
- Enhanced risk identification and aggressive treatment protocols are necessary to combat cardiovascular disease.
Abstract:
Vascular disease is basically an inherited metabolic disease. Eighty percent of individuals who develop disease have the same blood cholesterol levels as individuals who do not develop disease. With vascular disease pervasive throughout the world and current assessment techniques insufficient to identify those at risk, use of a multifactorial approach to vascular assessment is prudent. Assays are currently available that enable health care providers to determine risk beyond those traditionally used. These "novel" risk factors appear to be additive (Brown, 2001; Rader, 2000a, 2002; Superko, 1995), and when combined with traditional factors, LDL can be adjusted to prevent disease. In individuals with established disease, these factors can be instrumental in identifying an appropriate treatment protocol for halting the progression of disease. To date, the health care establishment as a whole has done a poor job of identifying and thoroughly treating cardiovascular risk. Even when risks were identified, often treatment protocols have not been aggressive enough to reach targeted goals (Hoerger, 1998; Jacobson, 2000; NHANES III, 2000). The unique role of the occupational health nurse offers an opportunity to follow a client during long periods of time. This is useful in establishing trust and getting to know the specific problems of each individual. The occupational health nurse, therefore, stands at the threshold of change for the client, easing and assisting the client to reach individual goals. This group of nurses can play a significant role in forging prevention and stamping out the number one killer of the American population.
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