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Fluoride concentrations in unerupted fluorotic human enamel
A Richards1, S Likimani, V Baelum
1Department of Oral Anatomy, Dental Pathology and Operative Dentistry, Royal Dental College, Aarhus, Denmark.
Caries Research
|January 1, 1992
Summary
Fluoride levels in unerupted teeth increase with dental fluorosis severity. This fluoride uptake occurs during tooth formation, with minimal additional absorption before eruption.
Area of Science:
- Dental science
- Biomineralization
- Fluoride toxicology
Background:
- Dental fluorosis is a condition resulting from excessive fluoride intake during tooth development.
- Understanding fluoride distribution in enamel is crucial for assessing its effects.
Purpose of the Study:
- To quantify fluoride concentrations in unerupted human enamel with varying degrees of dental fluorosis.
- To investigate the relationship between fluoride profiles, fluorosis severity, and enamel depth.
Main Methods:
- Serial acid etching of unerupted fluorotic enamel blocks (buccal and lingual surfaces).
- Fluoride concentration analysis using chemical methods.
- Assessment of fluorosis severity using the TF index, macroscopic, and microradiographic examination.
Main Results:
- Fluoride profiles in enamel were independent of fluorosis severity.
- Higher fluoride concentrations correlated with increased fluorosis severity.
- Fluoride levels in unerupted enamel matched those in erupted fluorotic enamel.
Conclusions:
- The fluoride content of fluorotic enamel is primarily acquired during tooth formation.
- Post-developmental fluoride uptake in enamel before eruption appears to be negligible.