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dictyBase: a new Dictyostelium discoideum genome database
Lisa Kreppel1, Petra Fey, Pascale Gaudet
1Laboratory of Cellular and Developmental Biology (50/3351), National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-8028, USA.
Nucleic Acids Research
|December 19, 2003
Summary
New online resources enhance Dictyostelium discoideum research. dictyBase and genome sequencing sites offer genomic and biological data for comparative genomics in metazoan organisms.
Area of Science:
- Cellular and Molecular Biology
- Genomics
- Bioinformatics
Background:
- Dictyostelium discoideum is a key model organism for studying cellular processes like chemotaxis and phagocytosis.
- Accessibility to Dictyostelium resources has significantly improved in recent years.
Purpose of the Study:
- To highlight the expansion and accessibility of online resources for Dictyostelium research.
- To introduce dictyBase as a comprehensive online resource for Dictyostelium data.
Main Methods:
- Development and integration of dictyBase with existing genome sequencing and assembly center websites.
- Consolidation of genomic data, functional annotation, and biological information.
Main Results:
- dictyBase provides access to functional gene annotation, gene products, and chromosomal mapping.
- The resource includes extensive biological information, such as mutant phenotypes and reference materials.
- Integration with other sites enhances data accessibility for researchers.
Conclusions:
- The improved and expanded Dictyostelium databases, including dictyBase, are valuable tools for researchers.
- These resources facilitate comparative and functional genomics studies in metazoan organisms.