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CADRE: the Central Aspergillus Data REpository.

J E Mabey1, M J Anderson, P F Giles

  • 1School of Medicine, University of Manchester, Manchester M13 9PT, UK. jane.mabey@man.ac.uk

Nucleic Acids Research
|December 19, 2003
PubMed
Summary
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The Aspergillus genomic data resource (CADRE) provides tools for analyzing fungal genomes, starting with Aspergillus fumigatus. It will expand to include other Aspergillus species, facilitating comparative genomics research.

Area of Science:

  • Mycology
  • Genomics
  • Bioinformatics

Background:

  • Maintaining and analyzing fungal genomic data is crucial for understanding species like Aspergillus.
  • Existing resources may lack comprehensive tools for genomic sequence analysis and visualization.
  • The Aspergillus fumigatus genome is a key focus for fungal research.

Purpose of the Study:

  • To establish a public resource for housing and analyzing genomic data from Aspergillus species.
  • To provide tools for searching, analyzing, and visualizing fungal genome features.
  • To enable the comparison of multiple Aspergillus genomes.

Main Methods:

  • Implementation of the CADRE resource using the Ensembl framework.
  • Integration of genomic data from Aspergillus fumigatus.

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  • Development of tools for data retrieval, analysis, and visualization.

    • Main Results:

    • CADRE is established as a public resource for Aspergillus genomic data.
    • The resource currently houses and analyzes the annotated genomic sequence of Aspergillus fumigatus.
    • A framework for storing and comparing multiple fungal genomes is in place.

    Conclusions:

    • CADRE provides a valuable platform for fungal genomics research.
    • The resource facilitates comparative genomics by enabling the inclusion of additional Aspergillus species.
    • Future expansion of CADRE will enhance its utility for the scientific community.