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Related Experiment Videos

LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as

Detlev Bannasch1, Alexander Mehrle, Karl-Heinz Glatting

  • 1German Cancer Research Center (DKFZ), Division of Molecular Genome Analysis, Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany. d.bannasch@dkfz.de

Nucleic Acids Research
|December 19, 2003
PubMed
Summary

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LIFEdb integrates human full-length cDNA data with functional genomics and proteomics information. This database aids researchers in exploring novel protein functions and experimental results.

Area of Science:

  • Genomics
  • Proteomics
  • Bioinformatics

Background:

  • The German cDNA Consortium generated novel human full-length cDNAs.
  • Functional genomics and proteomics approaches yield protein information.
  • Linking cDNA and protein data is crucial for understanding protein function.

Purpose of the Study:

  • To implement LIFEdb, a database linking human full-length cDNA information with functional protein data.
  • To provide a sample-tracking system for managing the cDNA-to-data process.
  • To facilitate the exploration and visualization of annotated cDNAs, ORFs, and experimental results for the scientific community.

Main Methods:

  • Implementation of the LIFEdb database.
  • Integration of data from the German cDNA Consortium.

Related Experiment Videos

  • Development of a web interface for data exploration and visualization.

    • Main Results:

    • LIFEdb successfully links human full-length cDNA sequences with functional protein data.
    • The database includes a sample-tracking system for experimental workflows.
    • A web interface allows visualization of annotated features and experimental outcomes.

    Conclusions:

    • LIFEdb serves as a valuable resource for researchers studying human proteins.
    • The integrated data helps in unraveling functions of proteins with unknown roles.
    • LIFEdb supports the exploration of novel protein features through combined experimental data.