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[Immunoglobulins in the treatment of herpes zoster]

G Agostini1, S Agostini

  • 1Instituto di Clinica Dermatologica, Università degli Studi di Pisa.

La Clinica Terapeutica
|September 1, 1992
PubMed

We have treated 20 patients with Herpes Zoster with "hyperimmune anti-Zoster immunoglobulins" (Uman-VZIG) by intralesional administration, 20 patients with Uman-VZIG by intramuscular administration and 23 patients with acyclovir by intravenous administration. The results of treatment in both groups of patients treated with Uman-VZIG were clinically satisfactory with disappearance of fever, local pain and amelioration of cutaneous lesions after two days from the start of treatment and with a mean duration of disease of five days. In patients treated with acyclovir, signs and symptomatology of disease ameliorated slowly and we have observed a longer mean duration of disease (about 8 days). We concluded that Uman-VZIG, both by intralesional and intramuscular administration, is effective and safe in Herpes Zoster treatment.

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