Related Experiment Video
Updated: Aug 5, 2026
07:37
A Rat Lung Transplantation Model of Warm Ischemia/Reperfusion Injury: Optimizations to Improve Outcomes
Published on: October 28, 2021
Lung transplantation for emphysema
Seth D Force1, Clifford Choong, Bryan F Meyers
1Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, GA 30322, USA.
Chest Surgery Clinics of North America
|December 20, 2003
Summary
Lung transplantation has advanced significantly, improving survival and function for patients with emphysema. This review covers current lung transplant techniques and outcomes, including insights from a decade of experience.
Area of Science:
- Cardiovascular Medicine
- Pulmonary Medicine
- Transplant Surgery
Background:
- Lung transplantation has seen major advancements over the last 20 years.
- Improvements in surgical techniques, immunosuppression, and infection management have enhanced patient outcomes.
- Key discussions involve single vs. bilateral sequential lung transplantation and donor lung allocation criteria.
Purpose of the Study:
- To review the current status of lung transplantation for emphysema.
- To provide insights based on over a decade of experience from Washington University's lung transplant program.
Main Methods:
- Review of current literature on lung transplantation for emphysema.
- Analysis of data and outcomes from Washington University's lung transplant program (over 10 years).
Main Results:
- Significant improvements in survival and functional results in lung transplantation.
- Ongoing debates regarding optimal surgical approach (single vs. bilateral) and donor lung allocation.
- Demonstrated experience and outcomes from a leading lung transplant center.
Conclusions:
- Lung transplantation is a viable and improving option for emphysema patients.
- Continued research and discussion are needed to refine techniques and allocation strategies.
- Washington University's program offers valuable experience in lung transplantation for emphysema.
Related Concept Videos
01:28Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
01:23Chronic Obstructive Pulmonary Disease II: Emphysema
Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.