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[Hepatic mesenchimal hamartoma in neonates]
E Esteves1, J A Goraib, J L Martins
1Universidade Federal de Goiás.
Jornal De Pediatria
|December 20, 2003
Summary
Hepatic mesenchymal hamartoma (HMH) in neonates requires surgical management due to potential fatal complications. Early diagnosis and prompt surgical intervention are crucial for favorable outcomes in these rare liver tumors.
Area of Science:
- Pediatric Surgery
- Neonatal Hepatology
- Surgical Pathology
Context:
- Hepatic mesenchymal hamartoma (HMH) is a rare benign liver tumor in neonates.
- HMH can present with diverse features, including giant cystic forms.
- Diagnosis and management can be challenging due to rarity and potential complications.
Purpose:
- To describe the diagnosis and management of two neonates with hepatic mesenchymal hamartoma (HMH).
- To highlight the diagnostic challenges and surgical approaches for neonatal HMH.
- To review the literature on HMH in newborns.
Summary:
- Two cases of neonatal HMH are presented: one with a ruptured giant hepatic cyst causing hypovolemic shock, managed with resection; the other with a progressively enlarging mass, treated with left hepatectomy.
- Histopathological and immunohistochemical analyses confirmed HMH in both cases, differentiating from hemangioma.
- Both neonates recovered well and remain asymptomatic.
Impact:
- Surgical management is essential for HMH as it does not resolve spontaneously.
- Timely surgical intervention can prevent life-threatening complications associated with giant HMH.
- Immunohistochemistry is vital for accurate pathological diagnosis, especially in differentiating cystic HMH from hemangioma.