Related Experiment Video

Updated: Aug 29, 2026

Methodology for Sputum Induction and Laboratory Processing
13:28

Methodology for Sputum Induction and Laboratory Processing

Published on: December 17, 2017

[Risk factors and clinical evolution of asthma in children]

I C Camelo-Nunes1, D Solé, C K Naspitz

  • 1Universidade Federal de São Paulo, Escola Paulista de Medicina.

Jornal De Pediatria
|May 1, 1997
PubMed

Insights

Pediatric asthma often begins in infancy and is frequently underdiagnosed. Key risk factors for childhood asthma include a family history of atopy, maternal asthma, and household smoking.

Area of Science:

  • Pediatric Allergy and Immunology
  • Respiratory Medicine
  • Clinical Epidemiology

Context:

  • Childhood asthma is a prevalent chronic respiratory condition.
  • Early identification of risk factors and clinical evolution is crucial for effective management.
  • This study focuses on outpatient pediatric allergy cases.

Purpose:

  • To investigate the clinical progression of asthma in children.
  • To identify significant risk factors associated with the development of asthma in pediatric patients.
  • To analyze precipitating factors for asthma exacerbations across different age groups.

Summary:

  • The study analyzed 165 children with asthma (ages 3-14) and 40 controls.
  • Symptoms often began in the first year of life, with initial triggers including infections and later allergens/irritants.
  • Significant risk factors identified were family history of atopy (RR=2.40), maternal asthma (RR=2.23), and household smoking (RR=2.30). Allergic rhinitis was a common co-occurrence.

Impact:

  • Highlights the underdiagnosis of asthma in children.
  • Provides evidence for specific genetic and environmental risk factors in pediatric asthma.
  • Informs clinical practice regarding early detection and preventative strategies for childhood asthma.
Abstract

Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma