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Stable T-cell population expressing an effector cell surface phenotype in the lungs of mice chronically infected with

Ana Paula Junqueira-Kipnis1, Joanne Turner, Mercedes Gonzalez-Juarrero

  • 1Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado 80523, USA. Ana.Kipnis@colostate.edu

Infection and Immunity
|December 23, 2003
PubMed

Analysis of T-cell subsets accumulating in the lungs of C57BL/6 mice chronically infected with Mycobacterium tuberculosis revealed that both CD4 and CD8 T-cell populations expressed a cell surface phenotype consistent with that of effector T cells and that a significant proportion of these cells were in the process of secreting gamma interferon.

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