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Congenital neonatal herpes simplex virus infection
B Sarkell1, W K Blaylock, H Vernon
1Department of Dermatology, Medical College of Virginia, Richmond 23298.
Journal of the American Academy of Dermatology
|November 1, 1992
Summary
Neonatal herpes simplex virus infection acquired in utero can be severe. This case highlights a rare epidermolysis bullosa-like presentation in a preterm infant, emphasizing the need for early diagnosis and treatment.
Area of Science:
- Neonatal infections
- Virology
- Dermatology
Background:
- Neonatal herpes simplex virus (HSV) infection is a severe condition with varied clinical manifestations.
- Intrauterine acquisition presents significant risks to the neonate.
Observation:
- A preterm male infant (31-week gestation) presented with an unusual epidermolysis bullosa-like rash.
- The infant's infection was acquired in utero via herpes simplex virus type II (HSV-II).
- Maternal primary infection occurred on the knee.
Findings:
- This case represents a rare clinical presentation of intrauterine HSV infection.
- Early recognition of atypical presentations is crucial for timely intervention.
Implications:
- Prompt diagnosis and initiation of antiviral therapy are essential for improving prognosis in neonatal HSV.
- Understanding diverse clinical presentations aids in managing severe neonatal infections.