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The technology behind Colgate Total Advanced Fresh.

Malcolm I Williams1, Diane Cummins

  • 1Colgate-Palmolive Company Technology Center, Piscataway, New Jersey, USA.

Compendium of Continuing Education in Dentistry (Jamesburg, N.J. : 1995)
|December 25, 2003
PubMed
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Colgate Total toothpaste, with triclosan and a copolymer, offers long-lasting protection against plaque, gingivitis, and bad breath for over 12 hours. This advanced formula also reduces tooth decay and tartar buildup.

Area of Science:

  • Oral hygiene
  • Dental therapeutics
  • Antimicrobial agents

Background:

  • Colgate Total toothpaste, introduced in the early 1990s, utilizes a combination of triclosan, polyvinylmethylether/maleic acid copolymer, and sodium fluoride.
  • The copolymer enhances oral retention and sustained release of triclosan, an antibacterial agent.

Purpose of the Study:

  • To evaluate the long-term efficacy of triclosan/copolymer toothpaste in controlling oral bacteria and preventing common dental issues.
  • To assess the impact of this toothpaste on plaque, gingivitis, calculus, caries, and halitosis.

Main Methods:

  • The study documents the prolonged presence of triclosan in the oral cavity for up to 12 hours post-brushing.
  • Long-term use (up to 2 years) was assessed for its effects on coronal caries and calculus formation.

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  • Comparison was made against an American Dental Association-Approved anticavity fluoride toothpaste.

    • Main Results:

    • Effective levels of triclosan were maintained in the oral cavity for 12 hours, enabling sustained control of odor-causing bacteria.
    • Significantly reduced incremental coronal caries were observed in users of the triclosan/copolymer toothpaste.
    • Reduced calcium levels in dental plaque led to decreased tartar formation.

    Conclusions:

    • The triclosan/copolymer toothpaste provides multiple oral health benefits, including prolonged control of bad breath and reduction in caries and calculus.
    • Colgate Total Advanced Fresh offers these therapeutic and esthetic benefits with an enhanced breath-freshening flavor.
    • Sustained control of bad breath for over 12 hours is a key feature of the new formulation.