Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiscale spike train variability in primary electrosensory afferents.

Mark E Nelson1

  • 1Beckman Institute for Advanced Science and Technology and Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, IL 61801, USA. m-nelson@uiuc.edu

Journal of Physiology, Paris
|December 25, 2003
PubMed
Summary

Analyzing spike train variability across multiple time scales reveals enhanced regularity in electric fish. This multiscale pattern improves signal detection and information transmission for electrolocation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Utility of Cry1Ja for Transgenic Insect Control.

Toxins·2024
Same author

Structural journey of an insecticidal protein against western corn rootworm.

Nature communications·2023
Same author

IPD072Aa from Pseudomonas chlororaphis Targets Midgut Epithelial Cells in Killing Western Corn Rootworm (<i>Diabrotica virgifera virgifera</i>).

Applied and environmental microbiology·2023
Same author

Enhancing global food security by using bacterial proteins with improved safety profiles to control insect pests.

Journal of invertebrate pathology·2021
Same author

Coordinated binding of a two-component insecticidal protein from Alcaligenes faecalis to western corn rootworm midgut tissue.

Journal of invertebrate pathology·2021
Same author

History of safe exposure and bioinformatic assessment of phosphomannose-isomerase (PMI) for allergenic risk.

Transgenic research·2021

Area of Science:

  • Neuroscience
  • Computational Neuroscience
  • Sensory Systems Biology

Background:

  • Spike train variability is crucial for neural information processing.
  • Traditional analyses focus on short-term variability (e.g., coefficient of variation).
  • Longer time scale variability remains less explored but is functionally relevant.

Purpose of the Study:

  • To investigate the functional importance of multiscale spike train variability.
  • To explore how spike train regularity on longer time scales impacts information processing.
  • To understand the mechanisms underlying spike train regularization in specific sensory neurons.

Main Methods:

  • Analysis of spike train variability across multiple time scales.
  • Modeling studies of probability coding (P-type) electrosensory afferent nerve fibers.

Related Experiment Videos

  • Investigation of dynamic spike threshold and relative refractory effects.

    • Main Results:

    • P-type afferent spike trains exhibit moderate short-term irregularity.
    • Significantly enhanced regularity is observed on longer time scales (hundreds of milliseconds).
    • This regularization exceeds predictions from uncorrelated renewal process models.

    Conclusions:

    • Multiscale spike train variability, particularly regularization on longer time scales, is functionally important.
    • Dynamic spike thresholds and refractory effects contribute to spike train regularization.
    • Regularized spike trains enhance signal detectability and information transmission for electrolocation.