Related Experiment Video
Updated: Aug 29, 2026

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
Published on: May 2, 2013
Influence of Th1, Th2, and Th3 cytokines during the early phase after liver transplantation
1Tianjin Institute of Thrombosis and Hemostasis, Organ Transplantation Center of Tianjin, First Central Hospital, 24 Fukang Road, Tianjin 300-192, P.R. China. wang_yu_l@yahoo.com.cn
Abstract:
To investigate the change of Th1, Th2, Th3 cytokines during early liver transplantation. IFN-r, IL-4, TGF-beta production by CD4+ T cells were determined by fluorescence activated cell sorter analysis. Comparing the acute rejection with the non-acute rejection groups on the 7th, 14th, and 28th day showed that high interferon-gamma production associated with acute rejection in the early posttransplant period. There was no evidence of significant changes in interleukin-4 and transforming growth factor beta (TGF-beta) levels between non-acute rejection groups with acute rejection groups. Th1 cytokine high production is significantly associated with acute rejection in liver transplant recipients.

