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Related Experiment Videos

[Local corticosteroid therapy in childhood].

M Wiesner1

  • 1Klinik für Hautkrankheiten, Universität Greifswald.

Kinderarztliche Praxis
|November 1, 1992
PubMed
Summary

Topical glucocorticoids (GC) treat childhood skin diseases but long-term use risks side effects. Discontinuous therapy or weaker GCs can minimize risks in pediatric patients.

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Area of Science:

  • Dermatology
  • Pediatrics
  • Pharmacology

Context:

  • Childhood dermatoses, including inflammatory and chronic skin conditions, often necessitate topical glucocorticoid (GC) treatment.
  • Long-term application of topical GCs in children increases the risk of both local and systemic side effects.
  • Pediatric skin possesses unique characteristics that influence GC absorption and potential adverse events.

Purpose:

  • To review the risks associated with topical glucocorticoid (GC) therapy in children.
  • To discuss factors influencing side effect profiles in pediatric patients.
  • To recommend strategies for minimizing adverse events during long-term GC treatment in childhood dermatoses.

Summary:

  • Topical glucocorticoids (GCs) are frequently used for pediatric inflammatory and chronic skin diseases.
  • Therapeutic risks escalate with prolonged use, influenced by children's skin properties, GC potency, and application methods.
  • Strategies like discontinuous therapy and utilizing weaker GCs are advised to mitigate adverse effects.

Impact:

  • Provides guidance for safer topical GC use in pediatric dermatology.
  • Aims to reduce the incidence of side effects in children undergoing long-term dermatological treatment.
  • Informs clinical practice regarding risk-benefit assessment for pediatric GC therapy.

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