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Related Experiment Videos

Asthma during pregnancy.

Mitchell P Dombrowski1, Michael Schatz, Robert Wise

  • 1Departments of Obstetrics and Gynecology at Wayne State University, Detroit, Michigan 48236, USA. Mitchell.Dombrowski@stjohn.org

Obstetrics and Gynecology
|January 6, 2004
PubMed
Summary

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This summary is machine-generated.

Pregnancy asthma severity did not significantly increase preterm birth risks. However, moderate to severe asthma correlated with a higher cesarean delivery rate and mild asthma with neonatal sepsis risk.

Area of Science:

  • Obstetrics and Gynecology
  • Pulmonology
  • Neonatology

Background:

  • Asthma is a common chronic respiratory condition affecting women of reproductive age.
  • Pregnancy can alter asthma control, potentially impacting maternal and neonatal outcomes.
  • Existing guidelines classify asthma severity to guide management.

Purpose of the Study:

  • To evaluate maternal and neonatal outcomes in pregnant individuals based on asthma severity.
  • To compare outcomes between non-asthmatic controls and those with mild, moderate, or severe asthma during pregnancy.

Main Methods:

  • A prospective, observational cohort study involving 16 university hospitals over 4 years.
  • Asthma severity was classified using National Asthma Education Program guidelines, modified for medication use.

Related Experiment Videos

  • Outcomes included preterm delivery (<32 and <37 weeks gestation), neonatal complications, and maternal complications.

    • Main Results:

    • No significant differences in preterm delivery rates (<32 or <37 weeks) were observed across asthma severity groups and controls.
    • Neonatal sepsis was more frequent in the mild asthma group compared to controls (aOR 2.9).
    • Cesarean delivery rates were higher in the moderate-to-severe asthma group compared to controls (aOR 1.4).

    Conclusions:

    • Pregnancy asthma, irrespective of severity, was not linked to increased preterm birth or most adverse perinatal outcomes.
    • Mild asthma showed a slight association with neonatal sepsis.
    • Moderate to severe asthma during pregnancy was associated with an increased rate of cesarean deliveries.