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Updated: Aug 18, 2026

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
[Prophylactic pan-coagulation from ischemic central vein occlusions? Practicability of the results from the Central
1Augenklinik der Ruprecht-Karls-Universität Heidelberg. ingo_schmack@med.uni-heidelberg.de
Purpose:
Central vein occlusions (CVO) with an avascular area of more than 10 optic-disc areas are classified as ischemic by the Central Vein Occlusion Study Group (CVOSG). For patients without neovascularizations (NV) clinical controls every 4 weeks during the first 6 months are recommended instead of prophylactic pancoagulation (PC). In this study we examined the practicability of this recommendation.
Patients And Methods:
We analysed the records of 15 patients with ischemic CVO and no clinical signs of NV and no prophylactic PC retrospectively. All these patients developed a neovascular glaucoma (NVG) despite using the criteria of the CVOSG and were then treated with cyclophotocoagulation (CPC).
Results:
The time between first presentation and CPC was 4.4+/-2.9 months. Of these patients 7 developed a NVG within 4 weeks after initial presentation.
Conclusions:
This study shows that NV and NVG may develop much faster than 4 weeks and can already be irreversible. Therefore it seems advisable to follow-up patients with increased risk factors even more frequently especially during the initial phase after CVO.
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