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Simple table for estimating confidence interval of discrepancy frequencies in microbiological safety evaluation
Brigitte Lamy1, Marie Laure Delignette-Muller, Florent Baty
1Laboratoire de bactériologie, Centre hospitalier Lyon-sud, Hospices Civils de Lyon F-69495 Pierre Benite Cedex, France. lamy@biomserv.univ-lyon.fr
Journal of Microbiological Methods
|January 7, 2004
Abstract:
We provide a simple tool to determine discrepancies confidence interval (CI) in microbiology validation studies such as technical accuracy of a qualitative test result. This tool enables to determine exact confidence interval (binomial CI) from an observed frequency when normal approximation is inadequate, that is, in case of rare events. This tool has daily applications in microbiology and we are presenting an example of its application to antimicrobial susceptibility systems evaluation.