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Updated: Jul 11, 2026

Comparing the Affinity of GTPase-binding Proteins using Competition Assays
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The GGA proteins: adaptors on the move

Juan S Bonifacino1

  • 1Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, Building 18T/Room 101, National Institutes of Health, Bethesda, Maryland 20892, USA. juan@helix.nih.gov

Nature Reviews. Molecular Cell Biology
|January 7, 2004
PubMed
Summary

The GGA proteins, Arf-dependent clathrin adaptors, are crucial for sorting mannose-6-phosphate receptors between cellular compartments. Recent research clarifies their binding interactions and roles in protein trafficking.

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