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Related Experiment Videos

Herbkines increases physical stamina in mice.

Hyun-Na Koo1, Jai-Kyoo Lee, Seung-Heon Hong

  • 1Department of Pharmacology, College of Oriental Medicine, Kyung Hee University, 1 Hoegi-Dong, Dongdaemun-Gu, Seoul 130-701, Korea.

Biological & Pharmaceutical Bulletin
|January 8, 2004
PubMed
Summary

Herbkines may improve physical stamina by reducing fatigue. Studies show it significantly decreased immobility time in mice during the forced swimming test and lowered blood urea nitrogen levels after two weeks of continuous administration.

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Area of Science:

  • Pharmacology
  • Exercise Physiology
  • Biochemistry

Background:

  • Herbkines is traditionally used to enhance physical strength.
  • Understanding its physiological effects on fatigue is crucial for athletic and therapeutic applications.

Purpose of the Study:

  • To investigate the effects of Herbkines on physical performance and fatigue-related biochemical markers in mice.
  • To evaluate Herbkines as a potential anti-fatigue agent.

Main Methods:

  • Oral administration of Herbkines (10 ml/kg daily) to mice for two weeks.
  • Assessment of physical performance using the forced swimming test (FST).
  • Measurement of blood biochemical parameters: blood urea nitrogen (BUN), creatine kinase (CK), lactic dehydrogenase (LDH), glucose (Glc), and total protein (TP).

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Main Results:

  • A significant decrease in immobility time during the FST was observed after two weeks of Herbkines administration.
  • Herbkines significantly reduced blood urea nitrogen (BUN) levels.
  • No significant changes were noted in creatine kinase (CK), lactic dehydrogenase (LDH), glucose (Glc), or total protein (TP) levels.

Conclusions:

  • Herbkines demonstrates potential as an anti-fatigue treatment.
  • The findings suggest Herbkines may improve physical stamina and endurance.