Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Factor V Leiden and contraception.

Lynette Ament1

  • 1Nurse-Midwifery Specialty, Yale University School of Nursing, New Haven, CT 06514, USA. lynette.ament@yale.edu

Journal of Midwifery & Women'S Health
|January 8, 2004
PubMed
Summary

Factor V Leiden is a common genetic mutation causing blood clots in women. A college student with a family history of clots tested positive, highlighting the need for genetic screening.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical education in managed care for advanced practice nurses: A case example.

Nurse education in practice·2008
Same author

Factor V Leiden: a review of the literature.

The Journal of perinatal & neonatal nursing·2003
See all related articles

Area of Science:

  • Genetics
  • Hematology
  • Thrombosis Research

Background:

  • Factor V Leiden is the most prevalent inherited thrombophilia.
  • It significantly increases the risk of venous thromboembolism (VTE), particularly in women.
  • Understanding its genetic basis is crucial for VTE prevention.

Observation:

  • A college-aged woman presented with symptoms suggestive of VTE.
  • She had a documented family history of venous thrombosis.
  • Genetic testing confirmed the presence of the Factor V Leiden mutation.

Findings:

  • The patient tested positive for the Factor V Leiden mutation.
  • This genetic predisposition explains her increased risk for VTE.
  • Diagnostic laboratory tests confirmed the thrombotic event.

Implications:

  • Early identification of Factor V Leiden is vital for managing VTE risk in young women.
  • Genetic screening in individuals with a family history of thrombosis is recommended.
  • Personalized anticoagulation strategies can be developed based on genetic findings.

Related Experiment Videos