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Establishment and Characterization of UTI and CAUTI in a Mouse Model
Published on: June 23, 2015
Structural and functional study of the receptor binding site for FimH adhesin in uropathogenic strains of Escherichia
1Russian University of People's Friendship; Washington State University, Seattle, USA.
Bulletin of Experimental Biology and Medicine
|January 10, 2004
Abstract:
We evaluated binding capacity of FimH-FocH hybrid adhesins during their interaction with model 1M and 3M substrates and epithelial cells. Introduction of the Glu89Lys point mutation into the fimH gene induced a new 1M-specific phenotype of adhesin. The role of a new pathoadaptive sign in the population of E. coli is discussed.
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