Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Radionuclide reporter gene imaging].

Zhen-wei Zhang1, Xue-mei Zhang, Hua Wu

  • 1Department of Nuclear Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. zwzhang@sibs.ac.cn

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
|January 13, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hypoxia promotes maintenance of the chondrogenic phenotype in rat growth plate chondrocytes through the HIF-1α/YAP signaling pathway.

International journal of molecular medicine·2018
Same author

Advantages of short repetition time resting-state functional MRI enabled by simultaneous multi-slice imaging.

Journal of neuroscience methods·2018
Same author

Local-scale determinants of arboreal spider beta diversity in a temperate forest: roles of tree architecture, spatial distance, and dispersal capacity.

PeerJ·2018
Same author

Uncommon Imaging Findings of Inflammatory Myofibroblastic Tumor: Report of a Rare Case With Both Omentum and Mesentery Involvement in the Abdominal Cavity.

Clinical nuclear medicine·2018
Same author

Time trends of incidence and mortality in colorectal cancer in Changning District, Shanghai, 1975-2013.

Journal of digestive diseases·2018
Same author

Galactose-Functionalized Double-Hydrophilic Block Glycopolymers and Their Thermoresponsive Self-Assembly Dynamics.

Langmuir : the ACS journal of surfaces and colloids·2018
Same journal

Splenic Angiosarcoma Misdiagnosed as PrimaryMyelofibrosis: Report of Two Cases and a Literature Review.

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae·2026
Same journal

Anesthetic Management for Epicardial Pacemaker Implantation in An Adult Patient With Uncorrected Functional Single Ventricle:A Case Report.

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae·2026
Same journal

Magnetic Resonance Imaging Combined With Ultrasonography for Early Diagnosis of Complete Hydatidiform Mole With Coexisting Fetus: Report of One Case.

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae·2026
Same journal

Prospects for China's Pharmaceutical Industry Development During the 15th Five-Year Plan Period.

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae·2026
Same journal

[Comparison of Imaging Efficacy and Patient Tolerability Between a Novel Cellulose-Based anda Conventional Starch-Based Oral Contrast Agent: A Prospective Randomized Controlled Trial].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae·2026
Same journal

[Application Value of Super-Resolution Ultrasound Imaging in the Diagnosisof American College of Radiology Thyroid Imaging Reporting and Data System Category 4 and 5 Thyroid Nodules].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae·2026
See all related articles

Molecular nuclear imaging tracks gene expression after gene therapy. Two main strategies use reporter genes for noninvasive imaging of gene activity.

Area of Science:

  • Molecular nuclear imaging
  • Gene therapy
  • Reporter gene technology

Context:

  • Developing noninvasive methods to monitor gene expression is crucial for gene therapy.
  • Current research focuses on radionuclide-based imaging strategies.
  • Understanding gene expression topography and levels post-therapy is essential.

Purpose:

  • To discuss two reporter gene imaging systems for detecting gene expression.
  • To review strategies using intracellular enzymes and cell-surface receptors.
  • To highlight noninvasive methods for gene expression analysis.

Summary:

  • Two radionuclide-based imaging strategies are explored for gene therapy monitoring.
  • Reporter genes encoding intracellular enzymes or cell-surface receptors are utilized.

Related Experiment Videos

  • These systems enable noninvasive detection of gene expression patterns.

    • Impact:

    • Facilitates the assessment of gene therapy efficacy.
    • Provides tools for precise mapping of gene expression.
    • Advances the field of molecular imaging in therapeutic applications.