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Updated: Aug 29, 2026

Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development
Published on: January 26, 2018
The physiology of uterine contractions
Holger Maul1, William L Maner, George R Saade
1Division of Reproductive Sciences, Department of Obstetrics & Gynecology, University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555, USA.
Studies in animals and humans indicate that uterine performance can be successfully monitored during pregnancy using uterine electromyography. Uterine electromyography could be used to better define management in a variety of conditions associated with human labor. The potential benefits of the proposed instrumentation and method include: reducing the rate of preterm delivery, improving maternal and perinatal outcome, monitoring treatment, decreasing cesarean-section rate, and providing research methods to better understand uterine function.
Studies in animals and humans indicate that uterine performance can be successfully monitored during pregnancy using uterine electromyography. Uterine electromyography could be used to better define management in a variety of conditions associated with human labor. The potential benefits of the proposed instrumentation and method include: reducing the rate of preterm delivery, improving maternal and perinatal outcome, monitoring treatment, decreasing cesarean-section rate, and providing research methods to better understand uterine function.
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