Related Experiment Video
Updated: Aug 29, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Higher age predicts adverse outcome and readmission after coronary artery bypass grafting
Otso Järvinen1, Heini Huhtala, Jari Laurikka
1Department of Cardiothoracic Surgery, Tampere University Hospital, Teiskontie 35, 33521, Tampere, Finland. otsojarvinen@koti.soon.fi
Insights
Older patients undergoing coronary artery bypass grafting (CABG) face higher mortality and complication risks. Age is a key predictor of adverse outcomes, but most elderly patients still recover well after CABG surgery.
Area of Science:
- Cardiovascular Surgery
- Geriatric Medicine
- Clinical Outcomes Research
Background:
- Coronary artery bypass grafting (CABG) is a common procedure for severe coronary artery disease.
- The impact of advanced age on outcomes following CABG requires further investigation.
Purpose of the Study:
- To evaluate the influence of patient age on mortality, morbidity, and readmission rates after CABG.
- To identify age as an independent predictor for adverse events post-CABG.
Main Methods:
- Prospective clinical study involving 1131 consecutive CABG patients.
- Data collected up to 3 months post-discharge, analyzed across three age groups: ≤64, 65-74, and ≥75 years.
Main Results:
- Thirty-day mortality rates increased with age (1.6% vs. 5.4% vs. 6.9%).
- Major complication rates were significantly higher in older age groups (10.8% vs. 21.2% vs. 24.9%).
- Readmission rates doubled in the oldest group (34.5%) compared to the youngest (18.6%), with atrial fibrillation being a common cause.
Conclusions:
- Elderly patients experience higher 30-day mortality, morbidity, and readmission rates after CABG.
- Advanced age is an independent predictor of 30-day mortality and post-discharge readmission.
- Despite increased risks, a majority of elderly patients achieve uneventful recovery post-CABG.
Abstract:
The present prospective clinical study was carried out to investigate the effect of age on mortality, morbidity, and readmission rates after coronary artery bypass grafting (CABG). Data on 1131 consecutive CABG patients were collected in a surgical center and in all 18 secondary referral hospitals up to 3 months after discharge. Analysis was based on three age groups: 64 years or less (510 patients), 65 to 74 years (448 patients), and 75 years or more (173 patients). Thirty-day mortality rates were 1.6% for the youngest, 5.4% for the middle age group, and 6.9% for the oldest. Major complications occurred in 10.8%, 21.2%, and 24.9% of these patients, respectively. Higher age was associated with more readmissions to health care facilities: The oldest patients had a rate twice as high as those in the youngest group (34.5% vs. 18.6%). Atrial fibrillation (15.4%), chest pain (10.6%), and congestive heart failure (8.5%) were the most common reasons for readmission. In conclusion, elderly patients, who are often suboptimal candidates for CABG, have higher 30-day mortality, higher morbidity, longer length of stay in health care facilities, and an increased risk of readmission within 3 months after CABG; age was an independent predictor of 30-day mortality and postdischarge readmission. Despite the higher risk of adverse events after surgery, three out of four elderly patients recover uneventfully.
Related Concept Videos
Coronary Artery Disease V: Interprofessional Care
Peripheral Artery Disease V: Postoperative Nursing Management
Coronary Artery Disease I: Introduction
