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Polymyalgia rheumatica is not seasonal in pattern and is unrelated to parvovirus b19 infection

Pilar Peris1

  • 1Department of Rheumatology, CAP Manso, Service of Rheumatology, Hospital Clinic of Barcelona, Villaroel 170, 08036 Barcelona, Spain.

The Journal of Rheumatology
|January 14, 2004
PubMed
Abstract

Insights

Polymyalgia rheumatica (PMR) symptom onset shows no seasonal pattern, despite nearly half of cases diagnosed in May, February, and August. Parvovirus B19 infection was not linked to PMR onset.

Area of Science:

  • Rheumatology
  • Infectious Disease Epidemiology

Background:

  • Polymyalgia rheumatica (PMR) is an inflammatory condition affecting individuals over 50.
  • Potential environmental triggers for PMR, such as viral infections, are being investigated.

Purpose of the Study:

  • To prospectively analyze the seasonal distribution of polymyalgia rheumatica (PMR) symptom onset.
  • To investigate the potential relationship between parvovirus B19 infection and PMR onset.

Main Methods:

  • Prospective diagnosis of 68 PMR patients over a 4-year period.
  • Analysis of symptom onset month for 55 patients.
  • Parvovirus B19 IgM serology testing in new cases during the final year.

Main Results:

  • No significant seasonal variation in PMR onset was observed (p = 0.625).
  • Nearly 50% of PMR cases were diagnosed in May, February, and August.
  • All tested patients (14/14) had negative parvovirus B19 IgM serologies, indicating no link to infection.

Conclusions:

  • Symptom onset in polymyalgia rheumatica (PMR) is not associated with seasonal patterns.
  • Parvovirus B19 infection does not appear to be a trigger for PMR onset.

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