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Epidemiology of vascular access for hemodialysis and related practice patterns
Rajiv Saran1, Ronald L Pisoni, William F Weitzel
1Division of Nephrology, Department of Internal Medicine and Kidney Epidemiology, Cost Center, University of Michigan, Ann Arbor, Mich., USA. rsaran@umich.edu
Insights
Vascular access (VA) is vital for hemodialysis (HD) patients, but practices vary globally. Optimizing VA placement and management, prioritizing arteriovenous fistulas (AVF), is key to improving patient survival and reducing costs.
Area of Science:
- Nephrology
- Vascular Surgery
- Healthcare Management
Background:
- Vascular access (VA) is essential for hemodialysis (HD) patients, representing a significant cost factor.
- Global variations in VA practices and outcomes are evident, impacting patient care.
- Patient and practice factors influence VA type selection and subsequent outcomes.
Purpose of the Study:
- To analyze global VA practices and outcomes in HD patients.
- To identify factors influencing VA type and patient survival.
- To emphasize the need for multidisciplinary approaches and further clinical trials in VA management.
Main Methods:
- Analysis of data from the Dialysis Outcomes and Practice Patterns Study (DOPPS).
- Examination of patient and practice pattern-related factors affecting VA placement and outcomes.
- Statistical adjustment for case mix to assess the association between VA type and patient survival.
Main Results:
- Wide variations in VA practices and outcomes exist worldwide.
- VA type is significantly associated with patient survival after adjusting for case mix.
- Arteriovenous fistula (AVF) is associated with better outcomes, while catheter use should be minimized.
Conclusions:
- A multidisciplinary approach, including pre-end-stage renal disease (ESRD) planning, is crucial for successful VA programs.
- AVF should be the preferred vascular access, with minimal reliance on catheters.
- Further clinical trials are necessary to optimize VA management and improve patient outcomes.
Abstract:
VA serves as a lifeline for HD patients. VA-related expenditures are the largest component of dialysis-related costs. Wide variations in VA practices and outcomes around the world have emerged from analysis of the DOPPS data. Both patient and practice pattern-related factors determine type of VA placed as well as VA outcomes. Type of VA is associated with patient survival after adjustment for case mix. A multidisciplinary approach is crucial for success of any VA program with emphasis on pre-ESRD planning and implementation. AVF should serve as the gold standard. Use of catheters should be minimal, but this will likely remain a challenge for some time. Observational data suggest that earlier cannulation of AVF may not be as deleterious as previously thought. Clinical trials are sorely needed in many aspects of VA management to improve both VA and patient outcomes.
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