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Sinonasal NK/T-cell lymphoma with upper gastrointestinal bleeding: a case report
Kuan-Jung Huang1, Ling-Feng Wang, Ka-Wo Lee
1Department of Otolaryngology, Kaohsiung Medical University, Kaohsiung, Taiwan.
The Kaohsiung Journal of Medical Sciences
|January 15, 2004
Summary
Sinonasal Natural Killer (NK)/T-cell lymphoma, a rare cancer, can spread to other body parts like the small intestine. This case highlights the importance of considering widespread disease in patients with this aggressive lymphoma.
Area of Science:
- Oncology
- Pathology
Background:
- Natural Killer (NK)/T-cell lymphoma is the most prevalent malignant lymphoma affecting the sinonasal region.
- Diagnosis and prognosis for sinonasal NK/T-cell lymphoma are challenging.
Observation:
- A 22-year-old male presented with nasal obstruction, facial swelling, and a palatal mass.
- Initial surgical intervention for the sinonasal tumor revealed NK/T-cell lymphoma.
- Post-operatively, the patient developed gastrointestinal bleeding due to a jejunal tumor, also identified as NK/T-cell lymphoma.
Findings:
- This case represents the first reported instance of NK/T-cell lymphoma originating in both the sinonasal region and the small intestine.
- Pathological examination confirmed identical NK/T-cell lymphoma in both the sinonasal and jejunal tumors.
Implications:
- The findings suggest that sinonasal NK/T-cell lymphoma can have extranodal involvement, extending to the gastrointestinal tract.
- This underscores the necessity for thorough systemic evaluation in patients diagnosed with sinonasal NK/T-cell lymphoma to detect potential distant metastases.