Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pertussis--a re-emerging infection?

K S C Fung1, W L Yeung, T W Wong

  • 1Department of Microbiology, Prince of Wales Hospital, Hong Kong, SAR, People's Republic of China. kittyfung@cuhk.edu.hk

The Journal of Infection
|January 15, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Professor Gerald Choa and the Hong Kong Museum of Medical Sciences.

Hong Kong medical journal = Xianggang yi xue za zhi·2026
Same author

The Guild of St Luke, St Cosmas and St Damian.

Hong Kong medical journal = Xianggang yi xue za zhi·2026
Same author

Training of medical laboratory technicians in Hong Kong.

Hong Kong medical journal = Xianggang yi xue za zhi·2025
Same author

The introduction of trained nurses at Government Civil Hospital in the nineteenth century.

Hong Kong medical journal = Xianggang yi xue za zhi·2025
Same author

Suyin Han and medical practice in the early 1950s Hong Kong.

Hong Kong medical journal = Xianggang yi xue za zhi·2024
Same author

Dr Kok-cheang Yeo (1903-2004): the first Chinese Director of Medical and Health Services in Hong Kong.

Hong Kong medical journal = Xianggang yi xue za zhi·2024
Same journal

Age-associated impairment of humoral and cellular immune responses to SARS-CoV-2 in a large community cohort with hybrid immunity.

The Journal of infection·2026
Same journal

Genomic characterization of a large-scale chikungunya outbreak in China.

The Journal of infection·2026
Same journal

Convergent neutralizing antibodies to SARS-CoV-2 variants over 2.5 years after BA.5/BF.7 breakthrough infection.

The Journal of infection·2026
Same journal

Multi-strain Clostridioides difficile infection: Increased detection and clinical implications.

The Journal of infection·2026
Same journal

A randomised comparison of management strategies for drug-induced liver injury associated with tuberculous meningitis treatment.

The Journal of infection·2026
Same journal

Defining the threshold duration of candidemia associated with poor outcomes: Redefining persistent candidemia.

The Journal of infection·2026
See all related articles

Infants under six months are at high risk for pertussis (whooping cough), even in vaccinated populations. Early diagnosis and prompt vaccination are crucial for protecting this vulnerable group.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Immunology

Background:

  • Pertussis (whooping cough) poses a significant threat to infants.
  • Herd immunity may not adequately protect vulnerable infants in highly vaccinated communities.

Purpose of the Study:

  • To report on pertussis cases in infants aged 1-6 months.
  • To highlight clinical indicators and emphasize vaccination strategies.

Main Methods:

  • Retrospective case series analysis of seven infants diagnosed with pertussis over three months.
  • Clinical data collection including symptoms, laboratory results (leukocyte and lymphocyte counts), and microbiological confirmation (Bordetella pertussis isolation).

Main Results:

  • Common symptoms included paroxysmal cough, post-tussive vomiting, and poor feeding.

Related Experiment Videos

  • Bordetella pertussis was confirmed in six out of seven cases.
  • Elevated lymphocyte counts (59-73%) were observed and suggested as potential diagnostic indicators.

    • Conclusions:

    • Infants aged 1-6 months are a vulnerable group for pertussis, requiring heightened clinical suspicion.
    • Maintaining high vaccination coverage and early infant vaccination are essential.
    • Prompt case identification, contact tracing, and timely treatment are critical for managing pertussis outbreaks.