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Related Experiment Videos

Body morphology differentially predicts coronary calcium.

M A Allison1, C Michael Wright

  • 1University of California at San Diego, 8950 Villa La Jolla Drive, Suite C203, La Jolla, CA 92037, USA. mallison@ucsd.edu

International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity
|January 16, 2004
PubMed
Summary

Body mass index (BMI) and visceral fat (VF) predict coronary artery calcification, especially in men. Weight control is crucial for preventing coronary heart disease.

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Area of Science:

  • Cardiology
  • Public Health
  • Medical Imaging

Background:

  • Coronary artery calcification (CAC) is a marker of atherosclerosis.
  • Body morphology, including body mass index (BMI), central adiposity (visceral fat - VF), and total body fat percentage (BF), may influence CAC.
  • Understanding these relationships is vital for coronary heart disease (CHD) prevention strategies.

Purpose of the Study:

  • To investigate the differential correlations and predictive power of BMI, VF, and BF on CAC.
  • To determine if body morphology measures are independent predictors of subclinical coronary atherosclerosis.

Main Methods:

  • A cross-sectional study involving 3028 healthy adults (mean age 56.7 years, mean BMI 27.0).
  • Measurements included coronary calcification and visceral fat (VF) via electron beam computed tomography, and body fat percentage (BF) via bioimpedance.

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  • Statistical analyses included correlation and multivariable logistic regression.

    • Main Results:

    • In men, higher BMI, VF, and BF were significantly associated with increased coronary calcium scores.
    • In women, only a high BMI was associated with increased coronary calcium risk.
    • Multivariable analysis confirmed BMI as a predictor in both genders, and VF as an independent predictor in men.

    Conclusions:

    • Body mass index (BMI) is a significant predictor of coronary artery calcification.
    • Central adiposity (visceral fat) is an independent predictor of CAC in men.
    • These findings underscore the importance of weight management for coronary heart disease prevention.