Cleft lip repair using intramuscular hydroxyzine sedation and local anesthesia

Intramuscular hydroxyzine was used alone for sedation in 18 cleft lip repairs with patients under 6 weeks of age. After injection of local anesthesia, the infants were quiet throughout the procedure. Blood pressure, pulse, respiration, and temperatures were normal throughout and the oxygen saturation remained above 94% in all cases. There were no complications noted with this series of patients and no patient required conversion to general anesthesia. Intramuscular hydroxyzine combined with local anesthesia and nerve block has been found to be a safe and effective method for cleft lip repairs in selected neonates under 6 weeks of age.