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Neural systems supporting interoceptive awareness.

Hugo D Critchley1, Stefan Wiens, Pia Rotshtein

  • 1Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, and Autonomic Unit, National Hospital for Neurology and Neurosurgery, University College London Hospitals, UK. h.critchley@fil.ion.ucl.ac.uk

Nature Neuroscience
|January 20, 2004
PubMed
Summary
This summary is machine-generated.

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This study shows the right anterior insula is crucial for awareness of bodily signals, impacting emotional intensity. Enhanced sensitivity to internal bodily responses is linked to subjective emotional experiences.

Area of Science:

  • Neuroscience
  • Psychology
  • Psychophysiology

Background:

  • Subjective emotional experiences are theorized to involve representations of bodily responses.
  • Individual differences in emotional intensity may stem from variations in sensitivity to these internal bodily signals.

Purpose of the Study:

  • To investigate the neural correlates of interoception and its relationship to emotional experience.
  • To identify brain regions involved in representing bodily responses accessible to awareness.

Main Methods:

  • Functional magnetic resonance imaging (fMRI) was used to measure brain activity during a heartbeat detection task.
  • Regional brain activity and gray matter volume were analyzed in relation to interoceptive accuracy and subjective awareness.

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Main Results:

  • Increased activity was observed in the insula, somatomotor, and cingulate cortices.
  • Neural activity and gray matter volume in the right anterior insula predicted interoceptive accuracy and visceral awareness.
  • Negative emotional experience correlated with interoceptive accuracy.

Conclusions:

  • The right anterior insula plays a key role in representing visceral bodily responses.
  • This representation in the right anterior insula provides a neural substrate for subjective emotional feeling states.