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Updated: Aug 11, 2026

Phosphopeptide Analysis of Rodent Epididymal Spermatozoa
Published on: December 30, 2014
Protein phosphatase 2A--a 'ménage à trois'
R E Mayer-Jaekel1, B A Hemmings
1Arbeitsgruppe für Zellbiologie-Tumorbiologie, Universität Konstanz, 78434 Konstanz, Germany.
Abstract:
Protein phosphorylation is probably the major regulatory mechanism employed by eukaryotic cells. Much work has been devoted to the role of protein kinases and their modulation by hormones, growth factors and neurotransmitters. It is now appreciated that protein phosphatases are also key players in actively regulating many cellular processes. In this article we discuss recent advances in our understanding of the function of protein phosphatase 2A, one of the major serine/threonine-specific protein phosphatases.
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