Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Two-component signal-transduction systems in budding yeast MAP a different pathway?

B A Morgan1, N Bouquin, L H Johnston

  • 1Division of Yeast Genetics at the National Institute for Medical Research, The Ridgeway, Mill Hill, London, NW7 1AA, UK.

Trends in Cell Biology
|December 1, 1995
PubMed
Summary

Two-component signal-transduction pathways, once thought exclusive to bacteria, are now found in eukaryotes like yeast. These pathways may regulate gene expression by influencing mitogen-activated protein kinase pathways.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of hydroxyurea on the mechanism of DNA synthesis in the yeast Saccharomyces cerevisiae.

Current genetics·2013
Same author

Newly synthesised DNA of high molecular weight in the yeast Saccharomyces cerevisiae.

Current genetics·2013
Same author

Broadband polarization rotator for the infrared.

Applied optics·2010
Same author

CD40 regulates the processing of NF-kappaB2 p100 to p52.

The EMBO journal·2002
Same author

The name of the game: a review of sexual exploitation of females in sport.

Current women's health reports·2002
Same author

Assembly and regulation of the cytokinetic apparatus in budding yeast.

Current opinion in microbiology·2001

Area of Science:

  • Microbiology
  • Molecular Biology
  • Cellular Signaling

Background:

  • Two-component signal-transduction pathways are well-established in prokaryotes.
  • Previously, these pathways were believed to be absent in eukaryotes.
  • Recent discoveries indicate eukaryotic occurrences, albeit less common than in bacteria.

Purpose of the Study:

  • To investigate the presence and function of two-component signal-transduction pathways in eukaryotes.
  • To understand how these pathways operate within eukaryotic cellular mechanisms.
  • To explore the relationship between eukaryotic two-component systems and other signaling cascades.

Main Methods:

  • Characterization of signaling pathways in Saccharomyces cerevisiae.
  • Comparative analysis of prokaryotic and eukaryotic signal transduction.

Related Experiment Videos

  • Investigation of gene expression regulation mechanisms.

    • Main Results:

    • Eukaryotic examples of two-component signal-transduction pathways have been identified.
    • In Saccharomyces cerevisiae, these pathways are less prevalent than in bacteria.
    • Eukaryotic two-component pathways appear to regulate gene expression via mitogen-activated protein kinase pathways.

    Conclusions:

    • Two-component signal-transduction is not exclusive to bacteria.
    • Eukaryotic two-component systems may function differently, integrating with existing signaling networks.
    • Further research is needed to fully elucidate the role of these pathways in eukaryotic cells.