Related Experiment Video

Updated: Aug 14, 2026

Microscopy of Fission Yeast Sexual Lifecycle
07:47

Microscopy of Fission Yeast Sexual Lifecycle

Published on: March 9, 2016

Nuclear migration advances in fungi

N R Morris1, X Xiang, S M Beckwith

  • 1Dept of Pharmacology, Robert Wood Johnson Medical School, University of Medicine and Dentistry, 675 Hoes Lane, Piscataway, NJ 08854, USA.

Trends in Cell Biology
|July 1, 1995
PubMed

Insights

This review focuses on interphase nuclear migration, essential for embryonic development and fungal growth. Molecular analysis of this process is advancing rapidly, utilizing insights from model organisms.

Area of Science:

  • Cell Biology
  • Molecular Biology
  • Genetics

Background:

  • Nuclear migration is a fundamental cellular process.
  • It is critical for various biological events, including embryonic development and fungal growth.
  • Three main types include nuclear separation during mitosis, nuclear congression before fertilization, and nuclear positioning in interphase.

Purpose of the Study:

  • To review the process of interphase nuclear migration.
  • To highlight its importance in diverse biological systems.
  • To discuss the molecular mechanisms being uncovered.

Main Methods:

  • Analysis of mutants in model organisms like Aspergillus nidulans, Neurospora crassa, and Saccharomyces cerevisiae.
  • Detailed molecular analysis of nuclear migration pathways.
  • Review of existing literature on nuclear positioning.

Main Results:

  • Interphase nuclear migration is crucial for development and growth.
  • Model organisms provide key insights into the molecular mechanisms.
  • Significant progress is being made in understanding the detailed molecular processes.

Conclusions:

  • Interphase nuclear migration is a vital and complex cellular process.
  • Genetic and molecular studies in fungi are key to understanding its mechanisms.
  • Further molecular analysis promises deeper insights into nuclear positioning.

More Related Videos

Examination of Mitotic and Meiotic Fission Yeast Nuclear Dynamics by Fluorescence Live-cell Microscopy12:04

Examination of Mitotic and Meiotic Fission Yeast Nuclear Dynamics by Fluorescence Live-cell Microscopy

Published on: June 24, 2019

Nuclear Migration in the Drosophila Oocyte04:17

Nuclear Migration in the Drosophila Oocyte

Published on: May 13, 2021

Related Concept Videos

Cell Migration01:09

Cell Migration

Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms throughout their life. When cells are not able to migrate properly to their ordained locations, various disorders may occur. For example, disruption in cell migration causes chronic inflammatory diseases such as arthritis.
Cell Migration01:19

Cell Migration

Cell migration is a process by which the cells move from one location to another, playing an essential role in embryological development, repair and regeneration, immune response, and metastasis. Cells migrate in response to chemical or mechanical signals generated by specific organs or tissues. The overall mechanism includes three steps - polarization, protrusion, and release. Polarization involves the formation of a distinct cell front and rear, which determines the direction of movement.
Cancer Cell Migration through Invadopodia01:35

Cancer Cell Migration through Invadopodia

Invadosome is a broad category of cell surface structures with proteolytic activity that  degrades the extracellular matrix (ECM). Invadosomes are present in normal cell types, including macrophages, endothelial cells, and neurons, as well as tumor cells. Although the macrophage podosomes and tumor cell invadopodia are classified as invadosomes, they have different structures, molecular pathways, and functions. Podosomes are short structures that last for a few minutes. However, invadopodia can...
Role of Myosin in Cell Migration01:18

Role of Myosin in Cell Migration

Myosins are multimeric motor proteins involved in various cellular processes such as migration, adhesion, and proliferation. Myosin II is the most common type in animal cells, which binds and cross-links actin filaments.
Myosin II  is a hexamer comprising two heavy chains with globular heads and coiled-coil tails, two regulatory light chains, and two essential light chains. The ATPase sites on the myosin heads hydrolyze ATP, and the released phosphate generates the force for contraction. It is...
Cytoskeletal Coordination in Cell Migration01:32

Cytoskeletal Coordination in Cell Migration

A migrating cell changes its shape during the cyclic events of attachment and detachment from the substratum and repositions the cell organelles correspondingly. These complex events are orchestrated by the dynamic cytoskeletal network comprising actin filaments, intermediate filaments, and microtubules. Cytoskeletal crosstalk — the direct and indirect communication between the different components — is crucial for this coordination. Direct communication involves various linker proteins that...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...