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Transverse myelitis in systemic sclerosis.

Amir M Torabi1, Rahul K Patel, Gil I Wolfe

  • 1Department of Neurology, the University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-8897, USA.

Archives of Neurology
|January 21, 2004
PubMed
Summary
This summary is machine-generated.

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Systemic sclerosis (SSc) rarely causes neurological issues. This study details a rare case of transverse myelitis in SSc, which improved with immunosuppressive treatment.

Area of Science:

  • Neurology
  • Rheumatology
  • Immunology

Background:

  • Neurological complications are uncommon in systemic sclerosis (SSc).
  • Transverse myelitis is a rare neurological manifestation reported in a limited number of SSc cases.

Observation:

  • A 30-year-old female patient with SSc presented with subacute onset of bilateral lower extremity weakness and numbness.
  • Diagnostic evaluations including MRI and cerebrospinal fluid analysis confirmed transverse myelitis.
  • No co-existing autoimmune disorders were identified in the patient.

Findings:

  • The patient received immunosuppressive therapy, including corticosteroids and cyclophosphamide.
  • Significant clinical recovery was observed following treatment.
  • Radiological abnormalities associated with transverse myelitis resolved.

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Implications:

  • Transverse myelitis is a rare but potential neurological manifestation of SSc.
  • Prompt immunosuppressive therapy can lead to favorable outcomes and recovery in SSc-associated transverse myelitis.