Related Experiment Video
Updated: Aug 29, 2026

A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
Published on: February 11, 2019
The ABCs of psychopharmacology
Norman L Keltner1, Frances J Kelley
1University of Alabama School of Nursing, Birmingham, AL, USA. KELTNER@son.uab.edu
Abstract:
The forgoing represents an attempt to reduce psychopharmacology to a presynaptic neuron-synapse-post-synaptic neuron event. Obviously other strategies might be employed resulting in equal or perhaps greater clarity. Limitations of this approach include the lack of discussion about neuronal modulation, second messenger systems (which most NTs discussed here use), expansion of the ion channel discussion, and the implications of excitatory vs. inhibitory physiological effects. Nonetheless, we find this template for understanding psychotropic drug mechanism of action a fruitful lens through which to guide further study of these drugs. We feel like we are moving toward a silver dollar-size circle.
Related Concept Videos
Drug Therapy
Antianxiety Medications
Psychosis: Goals of Pharmacotherapy
Psychosis and Antipsychotic Drugs: Overview
Antipsychotic Drugs: Typical and Atypical Agents
Introduction to Biological Bases of Psychology
The nervous system, the cornerstone of...
Antidepressant Drugs: Overview

