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Consensus conference on chronic viral hepatitis and HIV infection: updated Spanish recommendations
V Soriano1, J M Miró, J García-Samaniego
1Service of Infectious Diseases, Hospital Carlos III, Madrid, Spain. vsoriano@dragonet.es
Insights
Updated guidelines address the management of chronic hepatitis B (HBV) and hepatitis C (HCV) in patients with human immunodeficiency virus (HIV). New treatments necessitate revised recommendations for coinfected individuals, focusing on HBV and HCV management strategies.
Area of Science:
- Hepatology
- Infectious Diseases
- Virology
Background:
- Chronic hepatitis B (HBV) and C (HCV) are significant causes of illness and death in people with human immunodeficiency virus (HIV).
- Advancements in antiviral therapies for HBV and HCV necessitate updated clinical guidance for coinfected patients.
Framework:
- A panel of Spanish experts convened to review fifteen key topics concerning HBV and HCV management in HIV-infected patients.
- Recommendations were developed for nine HCV-related, five HBV-related, and one coinfection-specific topic.
- The Infectious Disease Society of America (IDSA) grading system was employed to score the proposed recommendations.
Implementation:
- The guidelines provide a comprehensive framework for managing coinfected patients.
- Expert consensus was reached on updated treatment strategies.
- The recommendations are designed for practical application in clinical settings.
Implications:
- These updated guidelines offer a crucial resource for clinicians managing coinfected patients.
- Improved management strategies can lead to better health outcomes for individuals with HIV and chronic viral hepatitis.
- This work supports the ongoing efforts to reduce morbidity and mortality associated with HBV and HCV in the HIV-positive population.
Abstract:
Chronic hepatitis B and C represent a leading cause of morbidity and mortality among human immunodeficiency virus (HIV)-infected patients worldwide. New treatment options against both hepatitis B (HBV) and C (HCV) viruses have prompted us to update previous recommendations for the management of coinfected individuals. Fifteen topics (nine related to HCV, five to HBV and one to both viruses) were selected for this purpose. A panel of Spanish experts in the field was invited to review these areas and propose specific recommendations, which were scored according to the Infectious Disease Society of America (IDSA) grading system. These guidelines represent a comprehensive and updated overview on the management of hepatitis B and C in HIV-infected patients.
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