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Septal perforation secondary to Mycobacterium kansasii infection
A M D Bennett1, N Patel, B Kotecha
1Departments of Otolaryngology and Pathology, Romford, UK. A1 bennett@hotmail.com
Abstract:
We report the first recorded case of a septal perforation caused by Mycobacterium kansasii. This atypical mycobacterium is finding increasing prevalence with the increasing incidence and longevity of human immunodeficiency (HIV) infections. Cases of chest infection, sinusitis, septic arthritis, osteomyelitis, pericarditis, brain abscess, cutaneous and oral lesions have all now been reported. This discovery represents a rare but important differential in the aetiology of septal perforation.
Insights
Mycobacterium kansasii, an atypical bacterium, has been identified as a rare cause of septal perforation. Its increasing prevalence, linked to human immunodeficiency virus (HIV) infections, makes it an important consideration in differential diagnoses.
Area of Science:
- Infectious Diseases
- Otolaryngology
- Microbiology
Background:
- Atypical mycobacterial infections are increasing due to rising human immunodeficiency virus (HIV) incidence and improved longevity.
- Various clinical manifestations of Mycobacterium kansasii infections have been documented, including respiratory, skeletal, and cutaneous conditions.
Observation:
- This report details the first documented instance of septal perforation directly attributed to Mycobacterium kansasii.
Findings:
- Mycobacterium kansasii can cause nasal septal perforation, a previously unreported manifestation.
- This finding expands the spectrum of clinical presentations associated with this atypical mycobacterium.
Implications:
- Septal perforation should be considered in the differential diagnosis of patients with Mycobacterium kansasii infection, especially those with HIV.
- This case highlights the need for broader diagnostic considerations in atypical mycobacterial infections.
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