Related Experiment Videos
Cell division: AAAtacking the mitotic spindle
Iain M Cheeseman1, Arshad Desai
1CMM-East, Rm 3071G, Ludwig Institute for Cancer Research, La Jolla, California 92093, USA. icheeseman@ucsd.edu
Current Biology : CB
|January 24, 2004
Abstract:
Cell division requires the assembly of a microtubule-based spindle which captures and segregates sister chromatids. But how is this spindle broken down once chromosome segregation is complete? New evidence implicates a highly conserved AAA-ATPase in spindle disassembly at the end of mitosis.