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Cervical myelitis from herpes simplex virus type 1.

Leena D Mewasingh1, Florence J C Christiaens, Bernard Dachy

  • 1Department of Paediatric Neurology, Hôpital Universitaire des Enfants Reine Fabiola, Université Libre de Bruxelles, Brussels, Belgium.

Pediatric Neurology
|January 24, 2004
PubMed
Summary
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A rare case of ascending paralysis in a child was linked to herpesvirus-1 infection of the spinal cord, mimicking Guillain-Barré syndrome. This highlights the importance of considering viral myelitis in pediatric neurological emergencies.

Area of Science:

  • Neurology
  • Pediatrics
  • Infectious Diseases

Background:

  • Ascending paralysis without sensory loss typically suggests Guillain-Barré syndrome.
  • Spinal cord inflammation or infection can also cause similar symptoms.

Observation:

  • A 16-month-old female presented with ascending flaccid paresis following an upper respiratory infection.
  • She developed both upper and lower motor neuron signs in her limbs.

Findings:

  • Electromyography and nerve conduction studies indicated anterior horn cell involvement.
  • Neuroimaging confirmed cervical myelitis.
  • Cerebrospinal fluid analysis revealed herpesvirus-1 positivity.

Implications:

  • Herpesvirus-1 myelitis is a critical differential diagnosis for pediatric ascending paralysis.

Related Experiment Videos

  • Neurotropic or hematogenous spread of herpesvirus-1 to the spinal cord is a potential mechanism.
  • Early diagnosis and management are crucial for pediatric neurological conditions.