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Thyroxine-induced hypermotor seizure
Adem Aydin1, A Pinar Cemeroglu, Baris Baklan
1Department of Pediatrics, Dokuz Eylül University Faculty of Medicine, Izmir, 35530 Karşiyaka, Turkey. adem.aydin@deu.edu.tr
Abstract:
Thyroxine-induced epilepsy is a very rare condition occurring in epileptic patients. Here we report a boy with thyroxine-induced hypermotor seizure (HMS) following thyroxine administration for his central hypothyroidism secondary to surgery and cranial radiation for his brain tumor. After 3 years seizure-free period, he had repeated HMS, seven to eight attacks per day, after initiation L-thyroxine treatment. Following reduction of the daily thyroxine dose, his seizures decreased in frequency. To our knowledge, this is the first reported case of HMS associated with L-thyroxine administration.
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