[Neuroprotective effect of cytoflavin in closed craniocerebral trauma]
V V Bul'on1, I V Zarubina, A L Kovalenko
1Department of Neuropharmacology, Institute of Experimental Medicine, Russian Academy of Medical Sciences, ul. akademika Pavlova 12, St. Petersburg, 197376 Russia.
Eksperimental'Naia I Klinicheskaia Farmakologiia
|January 28, 2004
Abstract:
The efficacy of a complex preparation cytoflavin was studied on rats with a model of closed craniocerebral trauma. Cytoflavin produced normalization of the energy exchange, lipid peroxidation, and antioxidant system functioning in nervous tissues. The treatment significantly reduced the degree of posttraumatic edemation in the brain. The cerebroprotective action of cytoflavin was somewhat superior to the effect of the reference drug solcoseryl.


