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Updated: Aug 29, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Mucoepidermoid carcinoma arising within nevus sebaceus of Jadassohn
A Hafeez Diwan1, Kathleen J Smith, R Brown
1Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
Background:
Nevus sebaceus (NS) of Jadassohn is a common congenital lesion associated with numerous benign and malignant tumors. However, mucoepidermoid carcinoma (MEC) has not been described in association with NS.
Methods:
We describe an unusual case of MEC arising within NS.
Results:
A 72-year-old man presented with an enlarging plaque on his forehead, along the hairline. Physical examination revealed a mounded, erythematous lesion that was completely excised. Histological evaluation revealed a typical MEC with areas of squamous and adenomatous differentiation with foci of typical intermediate cells.
Conclusion:
The diagnosis of MEC is an important one, because it portends a poor prognosis, requiring long follow-up. This is, to our knowledge, the first report of MEC arising within NS.
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