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Permanent-wave dermatitis: contact allergy to cysteamine hydrochloride
Maeran C Landers1, Sandra Law, Frances J Storrs
1Department of Dermatology, Oregon Health & Science University, Portland, OR, USA.
Summary
Cysteamine hydrochloride (CHC) is a newly identified sensitizer in permanent-wave solutions. A hairdresser allergic to CHC showed positive patch tests, but latex gloves offered protection.
Area of Science:
- Dermatology
- Allergology
- Cosmetic Chemistry
Background:
- Cysteamine hydrochloride (CHC) is increasingly used in permanent-wave solutions.
- Identifying new sensitizers in cosmetic products is crucial for public health.
Observation:
- A hairdresser presented with an allergic reaction to permanent-wave solutions.
- Patch testing revealed allergies to CHC, thioglycolates, and p-phenylenediamine (PPD).
- Latex gloves provided protection against CHC-induced allergic reactions.
Findings:
- The patient exhibited positive patch test reactions specifically to CHC.
- Control subjects showed no allergic reactions to CHC.
- Household latex gloves were found to be effective barriers against CHC sensitization.
Implications:
- CHC is a significant contact allergen in permanent-wave solutions.
- Occupational exposure in hairdressers necessitates protective measures like gloves.
- Further research into CHC's allergenic potential and safe usage is warranted.