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Photocontact allergy to diallyl disulfide
Marcy S Alvarez1, Stacy Jacobs, S Brian Jiang
1Department of Dermatology, New York University School of Medicine, New York, NY 10016, USA.
Summary
Photoallergic contact dermatitis from plants is rare. Diallyl disulfide, found in garlic, should be included in photopatch testing for suspected photosensitivity due to positive results in three patients.
Area of Science:
- Dermatology
- Allergology
- Photobiology
Background:
- Phototoxic plant reactions are common, but photoallergic contact dermatitis is rare.
- Photosensitivity evaluation typically involves phototests and patch tests for various allergens.
Observation:
- Phototests (UVB, UVA, visible light) and photopatch tests were conducted on 49 allergens.
- Three patients exhibited positive photopatch test reactions to diallyl disulfide.
Findings:
- Diallyl disulfide, a component of garlic, was identified as a rare photoallergen.
- Positive photopatch test results indicate photocontact allergy to diallyl disulfide.
Implications:
- Diallyl disulfide should be incorporated into standard photopatch test series.
- This inclusion aids in diagnosing rare cases of photocontact allergy to plant-derived substances.