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Triptorelin versus cetrorelix in intracytoplasmic sperm injection cycles in women with a single ovary
N Nikolettos1, B Asimakopoulos, K Diedrich
1Laboratory of Reproductive Physiology, Faculty of Medicine, Demokritus University of Thrace, Dragana, Hellas, 68100 Alexandroupolis, Greece.
Objective:
To compare the response to ovarian stimulation with either the long protocol of a GnRH-agonist or the multiple protocol of a GnRH-antagonist, in women with a single ovary who underwent intracytoplasmic sperm injection (ICSI) cycles.
Study Design:
Retrospective study including 75 ICSI cycles from 26 women. Sixty-three cycles were stimulated with triptorelin/hMG or rFSH, whereas 12 cycles were stimulated with cetrorelix/hMG or rFSH.
Results:
There was not found any statistical significant difference between the two groups regarding the days of stimulation, the number of gonadotropins' ampoules, the peak estradiol levels, the number of aspirated follicles and the number of retrieved oocytes. The fertilization rate, the number of transferred embryos as well as the cumulative embryo score were also similar in both groups.
Conclusion:
The multiple stimulation protocol of cetrorelix is equally effective with the long protocol of triptorelin in the ovarian stimulation of women with a single ovary.
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